Thomas Tuchel will not be on the sidelines due to being sent to the stands in Bayern’s final Champions League game of last season.
And Kingsley Coman could be unavailable too after missing Friday’s draw with Bayer Leverkusen with a muscular injury.
Legendary German keeper Manuel Neuer is also out of action after breaking his leg in December.
However, the Bayern boss is expecting to welcome new signing Raphael Guerreiro back after a muscular injury, while Harry Kane will most certainly start up top against his former Premier League rivals.
However, United have confirmed that Aaron Wan-Bissaka is out for a “few weeks” with a hamstring concern.
Furthermore, Jadon Sancho and Antony are expected to miss out due to off-field issues.